Note from Mr. W, 10/13/21. If you’re on this page and seeing this message, then you’re one of the first people to learn this material on Learn-Biology.com. If you see any typos or glitches in the quizzes, please let me know.

Here are a few more genetic patterns and phenomena to know about.

1. Mitochondrial Inheritance

Two mitochondria.
A model showing the incorporation of a proto-mitochondrion (at 2) into an archaeal host (at 1). You can learn more about the endosymbiotic theory at this tutorial.

All of the genetics we’ve learned about so far is the result of inheritance of genes residing on chromosomes which are found in the nucleus. These genes are known as nuclear genes, and they make up the vast majority of genes.

However, in all eukaryotes there’s one organelle — the mitochondrion — that contains its own genes. That’s because mitochondria are endosymbionts. Though our mitochondria are completely dependent upon us, they are, essentially, cells that live inside our cells. According to the endosymbiotic theory, mitochondria were once independent bacterial cells that took up residence inside what was probably an archaeal cell. In the partnership that ensued, the mitochondria found a home and a supply of food.  The archaeal host — which evolved into the entire domain of eukaryotes, including us — found an abundant way to make ATP. Over the last 1.8 billion years of endosymbiotic partnership, many mitochondrial genes have migrated into chromosomes within the nucleus.  But every mitochondria still contains dozens of copies of its own DNA genome: a loop of DNA consisting of 16,569 base pairs coding for 37 genes.

 

The cellular basis of mitochondrial inheritance. None of the sperm’s mitochondria enter into the egg.

Mitochondrial genes are inherited solely through the mother. Why? It’s about what happens during fertilization. Even though sperm cells contain mitochondria (2), these mitochondria do not become part of the zygote (the fertilized egg). Hence, the male’s genetic contribution to the offspring consists of his haploid genome only (1) , and not his mitochondrial genes. The female, by contrast, contributes both her haploid set of nuclear genes (5) and her mitochondria (6).

The mitochondrial electron transport chain.

What are these 37 mitochondrial genes? Fourteen are protein-coding genes related to cellular respiration. They code for the subunits of ATP synthase (6 at right), cytochrome c (a protein in the mitochondrial electron transport chain) and NADH dehydrogenases (the enzymes that harvest electrons from NADH, converting it to NAD+). The rest of the genes code for the small and large subunits of the mitochondrial ribosome, and for 22 mitochondrial tRNAs.

Mitochondrial DNA has a higher mutation rate than nuclear genes, and mutations in mitochondrial genes are associated with a variety of diseases. One such group of diseases are called mitochondrial myopathies, which have their primary effect upon nervous and muscle tissue. You can read more about these on Wikipedia.

Because mitochondria are passed through egg cells only (with no contribution from the sperm), mitochondrial genes have a unique inheritance pattern.

A pedigree showing mitochondrial inheritance

In row I, we see a mother (I-2) with a mitochondrial condition. Such conditions are passed by the mother to all of her offspring: hence I-2’s sons at II-1 and II-5 and her daughters at II-3 and II-7 all inherit the condition. In the next generation, we see that the sons at II-1 and II-5 do not pass the condition on to their offspring, but the daughters (II-3 and II-7) pass it on to all of their offspring.

Chloroplasts in moss leaf cells.

Plant cells also have mitochondria, plus an additional endosymbiont: the chloroplast. Like mitochondria, chloroplasts also have their own DNA. This DNA codes for about 110 genes.

Chloroplast genes code for proteins related to photosynthesis, and for RNAs and proteins involved in gene expression (ribosomes, tRNAs, etc.). In the same way that the sperm cells in animals don’t contribute mitochondrial genes, pollen doesn’t contribute chloroplast genes (or mitochondrial genes). So in plants we have a situation where the ovum (egg cell) contributes a haploid genome, mitochondrial DNA, and chloroplast DNA to the fertilized egg, while the pollen contributes only a haploid genome.

[qwiz qrecord_id=”sciencemusicvideosMeister1961-mitochondrial inheritance”]

[h] Mitochondrial Inheritance

[i]

A mitochondrion. The genes are in a loop of DNA at number 3.

 

[q multiple_choice=”true”] Because of mitochondrial genes, you’re more closely related to your

[c]IHNpc3RlciB0aGFuIHlvdSBhcmUgdG8geW91ciBicm90aGVy[Qq]

[f]IE5vLiBBbGwgc2libGluZ3MgaW5oZXJpdCBhYm91dCA1MCUgb2YgdGhlIHRoZWlyIG51Y2xlYXIgZ2VuZXMgZnJvbSB5b3VyIHBhcmVudHMsIGFuZCAxMDAlIG9mIHRoZWlyIG1pdG9jaG9uZHJpYWwgZ2VuZXMgZnJvbSB0aGVpciBtb3RoZXJzLiBJdCBkb2VzbiYjODIxNzt0IG1hdHRlciBpZiB0aGF0IHNpYmxpbmcgaXMgbWFsZSBvciBmZW1hbGUu[Qq]

[c]IGJyb3RoZXIgdGhhbiB5b3UgYXJlIHRvIHlvdXIgZmF0aGVyLg==[Qq]

[f]IE5vLiBZb3Ugc2hhcmUgZXhhY3RseSA1MCUgb2YgeW91ciBudWNsZWFyIGdlbmVzIHdpdGggeW91ciBmYXRoZXIuIFlvdSBzaGFyZSBhYm91dCA1MCUgb2YgeW91ciBudWNsZWFyIGdlbmVzIHdpdGggeW91ciBicm90aGVyLCBwbHVzIDEwMCUgb2YgeW91ciBtaXRvY2hvbmRyaWFsIGdlbmVzLiBTbyB5b3UmIzgyMTc7cmUgYSBiaXQgY2xvc2VyIChnZW5ldGljYWxseSkgdG8geW91ciBicm90aGVyIHRoYW4geW91ciBmYXRoZXIu[Qq]

[c]IG1vdGhlciB0aGFuIHlvdSBh cmUgdG8geW91ciBmYXRoZXIu[Qq]

[f]IEV4YWN0bHkuIFlvdSBzaGFyZSBleGFjdGx5IDUwJSBvZiB5b3VyIG51Y2xlYXIgZ2VuZXMgd2l0aCB5b3VyIG1vdGhlciBhbmQgeW91ciBmYXRoZXIgKHdobyBzaGFyZWQgdGhlbSB3aXRoIHlvdSB0aHJvdWdoIHRoZWlyIGVnZyBhbmQgc3Blcm0gY2VsbHMuIEJ1dCB5b3Ugc2hhcmUgMTAwJSBvZiB5b3VyIG1vdGhlciYjODIxNztzIG1pdG9jaG9uZHJpYWwgZ2VuZXMsIGFuZCBub25lIG9mIHlvdXIgZmF0aGVyJiM4MjE3O3MgbWl0b2Nob25kcmlhbCBnZW5lcy4=[Qq]

 

[q] According to the diagram below, you inherit all of your mitochondria from your mother’s [hangman], but none from your father’s [hangman].

[c]IGVnZw==[Qq]

[c]IHNwZXJt[Qq]

[q] Mitochondria that you don’t inherit are indicated by number

[textentry single_char=”true”]

[c]ID I=[Qq]

[f]IE5pY2UuICYjODIyMDsyJiM4MjIxOyBhcmUgbWl0b2Nob25kcmlhIGluIHRoZSBzcGVybSwgd2hpY2ggZG9uJiM4MjE3O3QgZ2V0IHBhc3NlZCBvbiB0byB0aGUgb2Zmc3ByaW5nLg==[Qq]

[c]IEVudGVyIHdvcmQ=[Qq]

[c]ICo=[Qq]

[f]IE5vLiBZb3UmIzgyMTc7cmUgbG9va2luZyBmb3IgbWl0b2Nob25kcmlhIHRoYXQgY29tZSBmcm9tIHlvdXIgZmF0aGVyLCBub3QgZnJvbSB5b3VyIG1vdGhlci4=[Qq]

[q] The mitochondria that you inherit are indicated by number

[textentry single_char=”true”]

[c]ID Y=[Qq]

[f]IENvcnJlY3QuICYjODIyMDs2JiM4MjIxOyBhcmUgbWl0b2Nob25kcmlhIGluIHRoZSBlZ2csIHdoaWNoIGFyZSB0aGUgb25lcyB0aGF0IGdldCBwYXNzZWQgb24gdG8gb2Zmc3ByaW5nLg==[Qq]

[c]IEVudGVyIHdvcmQ=[Qq]

[c]ICo=[Qq]

[f]IE5vLiBZb3UmIzgyMTc7cmUgbG9va2luZyBmb3IgbWl0b2Nob25kcmlhIHRoYXQgY29tZSBmcm9tIHlvdXIgbW90aGVyLiBMb29rIGluIHRoZSBlZ2cgY2VsbC4=[Qq]

[q multiple_choice=”true”]In the pedigree chart below, you know that the inheritance is not mitochondrial because

[c]VGhlIG1vdGhlciBpbiBnZW5lcmF0aW9uIEkgcGFzc2VkIG9uIHRoZSB0cmFpdCB0byBhbGwgb2YgaGVyIG9mZnNwcmluZy4=[Qq]

[f]Tm8uIFRoYXQmIzgyMTc7cyBhIGNvcnJlY3Qgc3RhdGVtZW50IGFib3V0IG1pdG9jaG9uZHJpYWwgaW5oZXJpdGFuY2UsIGJ1dCBpdCYjODIxNztzIG5vdCB3aGF0JiM4MjE3O3MgaGFwcGVuaW5nIGluIHRoaXMgcGVkaWdyZWUuIFRoZSBtb3RoZXIgZG9lc24mIzgyMTc7dCBoYXZlIHRoZSB0cmFpdCwgYnV0IGFsbCBvZiBoZXIgb2Zmc3ByaW5nIGRvIGhhdmUgaXQuIEluIG1pdG9jaG9uZHJpYWwgaW5oZXJpdGFuY2UsIHRoZSBtb3RoZXIgcGFzc2VzIHRoZSB0cmFpdCBvbiB0byBhbGwgb2YgaGVyIG9mZnNwcmluZy4=[Qq]

[c]VGhlIG1vdGhlciBpbiBnZW5lcmF0aW9uIElJIChJSS0zKSBvbmx5IHBhc3NlZC BvbiBoZXIgdHJhaXQgdG8gdGhyZWUgb2YgaGVyIGZpdmUgb2Zmc3ByaW5nLg==[Qq]

[f]VGhhdCYjODIxNztzIGNvcnJlY3QuIEluIG1pdG9jaG9uZHJpYWwgaW5oZXJpdGFuY2UsIHRoZSBtb3RoZXIgcGFzc2VzIG9uIGhlciB0cmFpdCB0byA=YWxsIG9mIGhlciBvZmZzcHJpbmcu[Qq]

[c]VGhlIGZhdGhlciBpbiBnZW5lcmF0aW9uIDEgcGFzc2VkIG9uIHRoZSB0cmFpdCB0byBhbGwgb2YgaGlzIG9mZnNwcmluZy4=[Qq]

[f]Tm8uIEluIG1pdG9jaG9uZHJpYWwgaW5oZXJpdGFuY2UsIHRoZSA=bW90aGVyIHBhc3NlcyBvbiBoZXIgdHJhaXQgdG8gYWxsIG9mIGhlciBvZmZzcHJpbmcu[Qq]

[q]Most mitochondrial genes are involved in mitochondrial gene expression or

[c]YWVyb2JpYyByZX NwaXJhdGlvbg==[Qq]

[f]WWVzLiBNaXRvY2hvbmRyaWFsIGdlbmVzIGFyZSBpbnZvbHZlZCBpbiBtaXRvY2hvbmRyaWFsIGdlbmUgZXhwcmVzc2lvbiBvciBjZWxsdWxhciByZXNwaXJhdGlvbi4=[Qq]

[c]cHJvdGVpbiBleHBvcnQu[Qq]

[f]Tm8uIFRoaW5rIG9mIGEgbWl0b2Nob25kcmlhbCBmdW5jdGlvbi4=[Qq]

[c]TWl0b3Npcw==[Qq]

[f]Tm8uIFRoaW5rIG9mIGEgbWl0b2Nob25kcmlhbCBmdW5jdGlvbi4=[Qq]

[q]The two organelles that contain their own genes are the [hangman], which are involved in cellular respiration, and the [hangman], which carries out photosynthesis.

[c]bWl0b2Nob25kcmlh[Qq]

[c]Y2hsb3JvcGxhc3Q=[Qq]

[/qwiz]

 

2. Incomplete Dominance

With incomplete dominance, we’re back to nuclear genes.

Let’s start with a widely known example of a new inheritance pattern. This occurs with inheritance of flower color in snapdragons. Answer the question below.

[qwiz]

[h]Crossing snapdragons (P generation)

[q] If a purebred red flowered snapdragon is crossed with a purebred white-flowered snapdragon, what color will the offspring be?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRoZSBvZmZzcHJpbmcgYXJlIHBpbmsu

Cg==

Cg==

[Qq]That’s not what you’d expect after learning about Mendel’s experiments with peas, where a true breeding purple and tree breeding white produce all purple flowers in the F1 generation. Let’s see what’s going on.

[/qwiz]

 

The inheritance pattern that’s at work in flower color inheritance in snapdragons is called incomplete dominance. Incomplete dominance occurs when the phenotype of a heterozygote is different from (and usually intermediate between) either of the homozygous phenotypes.

In snapdragons, neither the red color allele or the white color allele is dominant. As a result, we adopt a different notation system.

  • CR represents the red flower color allele.
  • CW represents the white flower color allele.

In a P generation cross between a homozygous red-flowered snapdragon (genotype CRCR) and a homozygous white flowered snapdragon (genotype CWCW), the offspring’s genotype is CRCW, and the phenotype is pink.

In the F1 cross between two pink heterozygotes (genotype CRCW), you get a phenotype (and genotype) ratio of 1 red offspring: two pink offspring: one white offspring.

On a molecular/cellular level, what’s happening with incomplete dominance? Let’s stick with snapdragons. For a snapdragon flow to be red, imagine that the cells in the flower need two doses of red pigment. To express that amount of pigment, you need to have both alleles, which only occurs in a homozygous red individual with genotype CRCR. Each one of these CR alleles is going to be read by RNA polymerase, and the resulting mRNAs are going to be expressed as red pigment protein, producing a bright red color.

Now, imagine the situation of the cells in a snapdragon heterozygote, whose genotype is CRCW. A single red pigment allele will be transcribed into mRNA, but only half as much red pigment protein is going to be produced in the heterozygotes as will be produced in a red homozygote. In this case, there’s not enough red pigment protein to produce a bright red color. Instead, we get pink.

That leads to an important insight. The difference between “traditional” dominance and incomplete dominance might depend on how closely you look. Think of sickle cell anemia. Looking at a an entire individual, from the outside, the sickle cell phenotype only shows up in homozygous recessives. But if you use a microscope and look at the blood of a heterozygote, you see that there’s some sickling that occurs in heterozygotes. And if you analyze the hemoglobin protein in heterozygotes, you find that about 60% of the hemoglobin is normal (HbA), and about 40% is the mutated version of the protein (HbS). That difference is evolutionarily important. It gives sickle cell heterozygotes resistance to malaria, a devastating tropical disease. That leads to natural selection for the sickle cell allele, increasing the frequency of this otherwise deadly allele in malaria-infested areas. You can learn more about this in this tutorial on Learn-Biology.com.

Here’s another example of incomplete dominance. in chickens the CB allele codes for black feathers, while the CW allele codes for white feathers. A heterozygote with genotype CBCW has blue feathers.

Knowing that, solve the following problems.

[qwiz qrecord_id=”sciencemusicvideosMeister1961-Incomplete dominance in chicken”]

[h]Solving incomplete dominance problems in chickens

[i]

[q]In a cross between two heterozygote chickens, genotype CBCW, the offspring will be

[c]MTAwJSBibHVlIGZlYXRoZXJlZA==[Qq]

[f]Tm8uIEhlcmUmIzgyMTc7cyBob3cgdG8gc2V0IHVwIHRoZSBQdW5uZXR0IHNxdWFyZQ==

Cg==Cg==Cg==Cg==
[Qq] CB CW
CB
CW

As with any Punnett square, bring the alleles in the gametes together to form the zygotes, and interpret the results.

[c]MTAwJSBXaGl0ZSBmZWF0aGVyZWQ=[Qq]

[f]Tm8uIEhlcmUmIzgyMTc7cyBob3cgdG8gc2V0IHVwIHRoZSBQdW5uZXR0IHNxdWFyZQ==

Cg==Cg==Cg==Cg==
[Qq] CB CW
CB
CW

As with any Punnett square, bring the alleles in the gametes together to form the zygotes, and interpret the results.

[c]NzUlIGJsYWNrIGZlYXRoZXJlZCwgMjUlIHdoaXRlIGZlYXRoZXJlZA==[Qq]

[f]Tm8uIEhlcmUmIzgyMTc7cyBob3cgdG8gc2V0IHVwIHRoZSBQdW5uZXR0IHNxdWFyZQ==

Cg==Cg==Cg==Cg==
[Qq] CB CW
CB
CW

As with any Punnett square, bring the alleles in the gametes together to form the zygotes, and interpret the results.

[c]NTAlIGJsdWUgZmVhdGhlcmVkLCAyNSUgYmxhY2sgZm VhdGhlcmVkLCAyNSUgd2hpdGUgZmVhdGhlcmVkLg==[Qq]

[f]RXhjZWxsZW50LiBIZXJlJiM4MjE3O3MgdGhlIFB1bm5ldHQgc3F1YXJl

Cg==Cg==Cg==Cg==
[Qq] CB CW
CB CBCB CBCW
CW CBCW CWCW

25% are black(CBCB), 50% blue (CBCW), and 25% white (CWCW)

[q]In a cross between a blue heterozygote chicken, genotype CBCW, and a white chicken, the offspring will be

[c]NTAlIGJsdWUsID UwJSB3aGl0ZQ==[Qq]

[f]V2F5IHRvIGdvISBIZXJlJiM4MjE3O3MgdGhlIFB1bm5ldHQgc3F1YXJlLg==

Cg==Cg==Cg==Cg==
[Qq] CB CW
CW CBCW CWCW
CW CBCW CWCW

50% of the offspring have the genotype CBCW and a blue feathered phenotype. The other 50% have the genotype CWCW,and a white feathered phenotype.

[c]MTAwJSBibGFjaw==[Qq]

[f]Tm8uIEhlcmUmIzgyMTc7cyBob3cgdG8gc2V0IHVwIHRoZSBQdW5uZXR0IHNxdWFyZQ==

Cg==Cg==Cg==Cg==
[Qq] CB CW
CW
CW

As with any Punnett square, bring the alleles in the gametes together to form the zygotes, and interpret the results.

[c]NTAlIGJsYWNrLCA1MCUgd2hpdGU=[Qq]

[f]Tm8uIEhlcmUmIzgyMTc7cyBob3cgdG8gc2V0IHVwIHRoZSBQdW5uZXR0IHNxdWFyZQ==

Cg==Cg==Cg==Cg==
[Qq] CB CW
CW
CW

As with any Punnett square, bring the alleles in the gametes together to form the zygotes, and interpret the results.

[/qwiz]

Another animal trait that shows incomplete dominance is the Palomino phenotype in horses, which comes about through crossing a Chesnut-coated horse and a Cremello-coated horse.

Courtesy of horsesandus.com.

Since humans are animals, it’s probable that many genes involve incomplete dominance (as with the sickle cell trait above). In terms of the easily observed traits that people seem to enjoy speculating about, it’s thought that wavy hair is due to incomplete dominance between alleles for curly hair and straight hair (though different sources explain this quite differently: click here for a reasonable discussion of hair texture from the Tech Museum in San Jose).

Height is a polygenic trait. This human height histogram was created by students and staff of Carnegie Mellon University for World Statistics Day. Original photo at http://gigapan.com/gigapans/62833.

However, note that height in humans is not an example of incomplete dominance. Rather, like many traits (intelligence, skin color, strength, athleticism, eye color and many more), human height is controlled by a variety of genes that interact in complex ways (and which are further influenced by the environment—see below). That makes human height a polygenic trait (a trait that’s under the influence of many interacting genes). That’s even true of a trait like free and attached earlobes. which is often taught as a case of simple Mendelian inheritance. In fact, a recent study indicates that earlobe attachment is polygenic, and might involve dozens of genes.

Finally, note that incomplete dominance works differently from the co-dominant pattern that we saw with blood type. In co-dominance, both alleles are completely expressed. For example, let’s look at the A, B, O blood type system. If you are a heterozygote who inherits an A allele and a B allele, then you express both the A and the B glycoprotein. There’s nothing in-between (in the way that pink is in between white and red).

To review co-dominance and blood type, please go to this tutorial.

3. Genotype-Environment Interaction

Hydrangeas are ornamental shrubs grown for their beautifully colored flower heads (which consist of dozens or hundreds of flowers) These can come in a variety of colors, as shown below.

Hydrangeas

What causes some hydrangeas to be blue, while others are red (or white)? After studying the inheritance of flower color in peas and snapdragons, a reasonable assumption would be that the color of these flower heads would be controlled by genes. But it’s not.

If you want blue hydrangeas in your garden, there’s a simple way to do that: make the soil in which your hydrangea is growing acidic. If you want red hydrangeas, make your soil basic. (To read more about the biology of hydrangea colors, read this article in the American Scientist).

The effect of the environment upon an organism’s genotype to bring about different phenotypes is called genotype environment interaction. The basic idea is that genes aren’t all powerful. Rather, the interaction between an organism’s genotype and its environment is what determines the phenotype of the organism.

Here’s another example from the plant world. Think of two trees, one growing deep in a forest, protected from wind, the second growing in an area exposed to the wind. The form of those trees will be different, with the wind exposed tree looking like what you see on the right.

Here’s an animal-related example. In the Himalayan rabbit, the black fur phenotype is only expressed in regions of the body that are exposed to cool temperatures (about 25° C). As a result, in warmer body regions (about 35° C) the fur color is white.
The result is a color pattern that looks like this in rabbits.
The same color pattern (called point coloration) occurs in Siamese cats, as well as many other mammals.
This color pattern can be experimentally manipulated.
  1. Start with a rabbit (or another animal) with the typical coloration patter.
  2. Shave a patch of fur off of what is typically a warmer body region, and place an cooling pack on that body region while the fur is growing back.
  3. When the fur has regrown, it’ll show the dark color typically shown in warmer body regions.

 

While the environment often influences gene expression and the resulting phenotype of an organism, in some cases the genotype is deterministic. Consider a few conditions that are determined by genes in humans. A child born as a homozygote for Tay-Sachs disease will die of that condition within a few years. If you inherit the allele for Huntington’s disease (a dominant allele), you’ll express the symptoms of this neurological disease sometime around middle age, and eventually die from it.

But even single gene-related disorders can be influenced by interaction with the environment. Read this passage from Wikipedia about phenylkenonuria, an enzyme deficiency disease.

Phenylketonuria (PKU) is a human genetic condition caused by mutations to a gene coding for a particular liver enzyme. In the absence of this enzyme, an amino acid known as phenylalanine does not get converted into the next amino acid in a biochemical pathway, and therefore too much phenylalanine passes into the blood and other tissues. This disturbs brain development leading to [intellectual disabilities] and other developmental problems.

PKU affects approximately 1 out of every 15,000 infants in the U.S. However, most affected infants do not grow up impaired because of a standard screening program used in the U.S. and other industrialized societies. Newborns found to have high levels of phenylalanine in their blood can be put on a special, phenylalanine-free diet. If they are put on this diet right away and stay on it, these children avoid the severe effects of PKU. This example shows that a change in environment (lowering Phenylalanine consumption) can affect the phenotype of a particular trait, demonstrating a gene–environment interaction.

 

Here’s an example on a population level. The graph to your left shows the average height of men in Japan between 1900 and 2012. What accounts for the rapid increase in height after 1945 (the end of World War II)?

The environment changed. After its defeat in World War II, the Japan’s culture became more influenced by American culture. This included adopting North American eating patterns, including a higher amount meat and fat in the diet. In response to this change, the mean phenotype of Japanese men changed (note: the average height of Japanese women increased as well, but by a smaller amount (source)).

To a large degree, the entire field of epigenetics is about genotype environment interactions, and their effects upon gene expression. To learn more about gene expression and epigenetics, you can to to this tutorial on Learn-Biology.com.

4. Cumulative Quiz

Got it? Take the quiz below.

[qwiz qrecord_id=”sciencemusicvideosMeister1961-Gene-env, inc. dom, mito inheritance cumulative quiz”]

[h]Incomplete dominance, Genotype -Environment Interaction, and mitochondrial inheritance

[i]

[q labels=”top”]

Genotype Phenotype Description
CRC _______ _______________
CWC _______ _______________
CRC _______ _______________

 

[l]pink

[fx] No, that’s not correct. Please try again.

[f*] Great!

[l]red

[fx] No, that’s not correct. Please try again.

[f*] Correct!

[l]white

[fx] No, that’s not correct. Please try again.

[f*] Excellent!

[l]homozygous

[fx] No, that’s not correct. Please try again.

[f*] Excellent!

[l]heterozygous

[fx] No. Please try again.

[f*] Good!

[q multiple_choice=”true”]In a cross between two pink snapdragons, the expected phenotype ratio is

[c]MTAwJSBwaW5r[Qq]

[f]Tm8uIFN0dWR5IHRoZSBQdW5uZXR0IFNxdWFyZSBiZWxvdyBhbmQgdHJ5IGFnYWluLg==

Cg==

[Qq]

[c]NTAlIHJlZDogNTAlIHdoaXRl[Qq]

[f]Tm8uIFN0dWR5IHRoZSBQdW5uZXR0IFNxdWFyZSBiZWxvdyBhbmQgdHJ5IGFnYWluLg==

Cg==

[Qq]

[c]MjUlIHJlZDogNTAlIHBp bms6wqAgMjUlIHdoaXRl[Qq]

[f]RXhjZWxsZW50ISBIZXJlJiM4MjE3O3MgdGhlIFB1bm5ldHQgc3F1YXJl

Cg==

[Qq]

[c]NzUlIHJlZDogMjUlIHdoaXRl[Qq]

[f]Tm8uIFN0dWR5IHRoZSBQdW5uZXR0IFNxdWFyZSBiZWxvdyBhbmQgdHJ5IGFnYWluLg==

Cg==

[Qq]

[q multiple_choice=”true”] Which of the following is the best definition of incomplete dominance?

[c]SW4gaGV0ZXJvenlnb3RlcywgdGhlIGRvbWluYW50IGFsbGVsZSBtYXNrcyB0aGUgZXhwcmVzc2lvbiBvZiB0aGUgcmVjZXNzaXZlIGFsbGVsZS4=[Qq]

[f]Tm8uIFRoYXQmIzgyMTc7cyBhIHByZXR0eSBnb29kIGRlZmluaXRpb24gb2YgaG93IGRvbWluYW50IGFuZCByZWNlc3NpdmUgYWxsZWxlcyB3b3JrLg==[Qq]

[c]SW4gaGV0ZXJvenlnb3RlcywgYm90aCBhbGxlbGVzIGFyZSBlcXVhbGx5IGV4cHJlc3NlZCBpbiB0aGUgcGhlbm90eXBlIG9mIHRoZSBvZmZzcHJpbmcu[Qq]

[f]Tm8uIFRoYXQmIzgyMTc7cyBhIGRlZmluaXRpb24gb2YgQ28tZG9taW5hbmNlLCBzdWNoIGFzIHdpdGggQUIgYmxvb2QgdHlwZS4gQm90aCB0aGUgQSBhbmQgdGhlIEIgcHJvdGVpbnMgYXJlIGV4cHJlc3NlZC4=[Qq]

[c]SW4gaGV0ZXJvenlnb3RlcywgdGhlIHBoZW5vdHlwZSBvZiB0aGUgaGV0ZXJvenlnb3RlwqAg aXMgaW50ZXJtZWRpYXRlIGJldHdlZW4gdGhlIHR3byBob21venlnb3VzIHBoZW5vdHlwZXMu[Qq]

[f]TmljZSBqb2IhIFRoYXQmIzgyMTc7cyBhIGdyZWF0IGRlZmluaXRpb24gb2YgaW5jb21wbGV0ZSBkb21pbmFuY2Uu[Qq]

[q multiple_choice=”true”]The most reasonable explanation for the pink color of heterozygous snapdragons is that

[c]VGhlIGhldGVyb3p5Z290ZXMgYXJlIGV4cHJlc3NpbmcgdG9vIG11Y2ggcmVkIHBpZ21lbnQsIHJlc3VsdGluZyBpbiB0aGVpciBwaW5rIGNvbG9yLg==[Qq]

[f]Tm8uIEhvdyBjb3VsZCB0b28gbXVjaCByZWQgcGlnbWVudCByZXN1bHQgaW4gYSBwaW5rPw==[Qq]

[c]VGhlIGhldGVyb3p5Z290ZXMgYXJlbiYjODIxNzt0IHByb2R1Y2luZyBl bm91Z2ggcmVkIHBpZ21lbnQgdG8gY3JlYXRlIHJlZCBmbG93ZXJzLg==[Qq]

[f]WWVzLiBXaXRoIG9ubHkgb25lIGFsbGVsZSBmb3IgcmVkLCB0aGVyZSYjODIxNztzIG5vdCBzdWZmaWNpZW50IHJlZCBwaWdtZW50IGJlaW5nIHByb2R1Y2VkIHRvIGNyZWF0ZSBhIGJyaWdodCByZWQgY29sb3Iu[Qq]

[c]VGhlIHdoaXRlIGFsbGVsZSBpbiB0aGUgaGV0ZXJvenlnb3RlcyBwcm9kdWNlcyBhIHByb3RlaW4gdGhhdCBibG9ja3MgZXhwcmVzc2lvbiBvZiB0aGUgcmVkIGFsbGVsZS4=[Qq]

[f]IE5vJiM4MjMwO0lmIHRoYXQgd2VyZSB0cnVlLCB0aGVuIHdoaXRlIHdvdWxkIGJlIGRvbWluYW50IG92ZXIgcmVkLiBDaG9vc2UgYW5vdGhlciBhbnN3ZXIu[Qq]

[q multiple_choice=”true”]The pedigree below is best explained by

[c]bWl0b2Nob25kcmlhbC Bpbmhlcml0YW5jZQ==[Qq]

[f]TmljZS4gWW91IGlkZW50aWZpZWQgdGhlIGtleSBwYXR0ZXJuOiB0aGUgbW90aGVyIHBhc3NlcyBvbiBoZXIgbWl0b2Nob25kcmlhbCBnZW5lcyB0byBhbGwgb2YgaGVyIG9mZnNwcmluZ3Mu[Qq]

[c]SW5jb21wbGV0ZSBkb21pbmFuY2U=[Qq]

[f]Tm8uIEhlcmUmIzgyMTc7cyBhIGRlZmluaXRpb24gZm9yIGluY29tcGxldGUgZG9taW5hbmNlOiBJbiBoZXRlcm96eWdvdGVzLCB0aGUgcGhlbm90eXBlIG9mIHRoZSBoZXRlcm96eWdvdGXCoCBpcyBpbnRlcm1lZGlhdGUgYmV0d2VlbiB0aGUgdHdvIGhvbW96eWdvdXMgcGhlbm90eXBlcy7CoA==SXQgZG9lc24mIzgyMTc7dCBzZWVtIGxpa2UgdGhlcmUmIzgyMTc7cyBhbnkgZXZpZGVuY2UgZm9yIGJsZW5kaW5nIG9mIHBoZW5vdHlwZXMu[Qq]

[c]c2V4IGxpbmtlZCBpbmhlcml0YW5jZQ==[Qq]

[f]Tm8uIEluIGEgc2V4IGxpbmtlZCB0cmFpdCwgYSBtYWxlIHBhc3NlcyBvbiBhbiBhbGxlbGUgdGhhdCByZXNpZGVzIG9uIGhpcyBYIGNocm9tb3NvbWUgdG8gaGlzIGRhdWdodGVycy4gQmVjYXVzZSB0aGUgYWxsZWxlIGlzIG9uIHRoZSBYIGNocm9tb3NvbWUsIHRoZSBtYWxlIGNhbiYjODIxNzt0IHBhc3MgaXQgb24gdG8gaGlzIHNvbnMuIFRoYXQgcGF0dGVybiBkb2VzbiYjODIxNzt0IHNlZW0gdG8gYmUgYXQgd29yayBoZXJlLg==[Qq]

[q]If an allele is on the DNA found at “1” or “5” below, we know that a gene coded for by that DNA can’t be [hangman].

[c]bWl0b2Nob25kcmlhbA==[Qq]

[q]A gene that’s passed on through mitochondrial inheritance would have to be on which number below?

[textentry single_char=”true”]

[c]ID Y=[Qq]

[f]IENvcnJlY3QuICYjODIyMDs2JiM4MjIxOyBhcmUgbWl0b2Nob25kcmlhIGluIHRoZSBlZ2csIHdoaWNoIGFyZSB0aGUgb25lcyB0aGF0IGdldCBwYXNzZWQgb24gdG8gb2Zmc3ByaW5nIGluIG1pdG9jaG9uZHJpYWwgaW5oZXJpdGFuY2U=[Qq]

[c]IEVudGVyIHdvcmQ=[Qq]

[c]ICo=[Qq]

[f]IE5vLiBZb3UmIzgyMTc7cmUgbG9va2luZyBmb3IgdGhlIG1pdG9jaG9uZHJpYSB0aGF0IGNvbWUgZnJvbSB5b3VyIG1vdGhlci4gTG9vayBpbiB0aGUgZWdnIGNlbGwu[Qq]

[q]A tall woman and a short man have a child of intermediate height. Though this looks like incomplete dominance, it’s not. That’s because height in humans is a [hangman] trait.

[c]cG9seWdlbmlj[Qq]

[q multiple_choice=”true”]Inheritance of blood types A,B, AB, or O is an example of

[c]cG9seWdlbmljIGluaGVyaXRhbmNl[Qq]

[f]Tm8uIFRoZXJlJiM4MjE3O3Mgb25seSBvbmUgZ2VuZSAodGhvdWdoIGl0IGhhcyBtdWx0aXBsZSBhbGxlbGVzKS4gVGhpbmsgYWJvdXQgaG93ICYjODIyMDtBJiM4MjIxOyBhbmQgJiM4MjIwO0ImIzgyMjE7IGFyZSBleHByZXNzZWQu[Qq]

[c]aW5jb21wbGV0ZSBkb21pbmFuY2U=[Qq]

[f]Tm8uIEluIGluY29tcGxldGUgZG9taW5hbmNlLCB5b3UgZ2V0IGFuIGludGVybWVkaWF0ZSBwaGVub3R5cGUuICYjODIyMDtBQiYjODIyMTsgaXMgbm90IGludGVybWVkaWF0ZSBiZXR3ZWVuIEEgYW5kIEI6aXQmIzgyMTc7cyBhIGZ1bGwgZXhwcmVzc2lvbiBvZiBib3RoLg==[Qq]

[c]Z2Vub3R5cGUtZW52aXJvbm1lbnQgaW50ZXJhY3Rpb24=[Qq]

[f]Tm8uIEJsb29kIHR5cGUgaXMgbm90IGluZmx1ZW5jZSBieSB0aGUgZW52aXJvbm1lbnQsIGJ1dCBvbmx5IGJ5IGdlbmVzLg==[Qq]

[c]Q28tZG9t aW5hbmNl[Qq]

[f]TmljZWx5IGRvbmUuIFRoZSBBQk8gYmxvb2QgdHlwZSBzeXN0ZW0gaXMgYW4gZXhhbXBsZSBvZiBDby1kb21pbmFudCBpbmhlcml0YW5jZS4=[Qq]

[q]The color of hydrangeas can be determined by the acidity of the soil that the hydrangea plant is growing in. That makes hydrangea coloration an example of genotype-[hangman] interaction.

[c]ZW52aXJvbm1lbnQ=[Qq]

[q multiple_choice=”true”]The color pattern on a siamese cat is best explained by which of the following.

[c]VGhlIGVuenltZSBmb3IgZXhwcmVzc2luZyBtZWxhbmluIChkYXJrIHBpZ21lbnQpIGlzIGRlbmF0dXJlZCBieSBjb2xkLCByZXN1bHRpbmcgaW4gZGFyayBmdXIgaW4gdGhlIGNvb2xlc3QgcGFydCBvZiB0aGUgYm9keS4=[Qq]

[f]Tm8uIElmIHRoZSBlbnp5bWUgZm9yIGRhcmsgcGlnbWVudCB3YXMgZGVuYXR1cmVkIGJ5IGNvbGQsIGhvdyBjb3VsZCBkYXJrIHBpZ21lbnQgYmUgZXhwcmVzc2VkIG9ubHkgaW4gdGhlIGNvb2xlc3QgcGFydCBvZiB0aGUgYm9keT8=[Qq]

[c]VGhlIGVuenltZSBmb3IgZXhwcmVzc2luZyBtZWxhbmluIGlzIHNlbnNpdGl2ZSB0byBncmF2aXR5LCBhbmQgb25seSBleHByZXNzZWQgaW4gdGhlIGxvd2VzdCBwYXJ0cyBvZiB0aGUgYm9keS4=[Qq]

[f]Tm8uIFRoYXQgbWlnaHQgbWFrZSBzZW5zZSBmb3IgdGhlIGZlZXQsIGJ1dCBub3QgZm9yIHRoZSBlYXJzLg==[Qq]

[c]VGhlIGVuenltZSBmb3IgZXhwcmVzc2luZyBtZWxhbmluIGlzIGFjdGl2YXRlZCBieSBjb29sZXIgdGVtcGVyYXR1cmVzLCBhbmQgb25s eSBleHByZXNzZWQgaW4gcGFydHMgb2YgdGhlIGJvZHkgdGhhdCBhcmUgZnVydGhlc3QgZnJvbSB0aGUgY29yZSBvZiB0aGUgYm9keS4=[Qq]

[f]WWVzLiBUaGF0JiM4MjE3O3Mgd2h5IHlvdSBoYXZlIHRoZSBwYXR0ZXJuIG9mIGNvb2xlciBib2R5IHBhcnRzIGhhdmluZyBkYXJrZXIgY29sb3JhdGlvbi4=[Qq]

[q]True or false: Genotype environment interaction only shows up in polygenic traits, like height, body weight, and overall intelligence.

[c]VHJ1ZQ==[Qq]

[f]Tm8uIEV2ZW4gdHJhaXRzIGNvbnRyb2xsZWQgYnkgc2luZ2xlIGdlbmVzLCBsaWtlIHRoZSBnZW5lIGZvciBQS1UgZGlzZWFzZSBjYW4gYmUgaW5mbHVlbmNlZCBieSB0aGUgaW5kaXZpZHVhbCYjODIxNztzIGVudmlyb25tZW50Lg==[Qq]

[c]RmFs c2U=[Qq]

[f]RXhjZWxsZW50LiBUaGUgZXhwcmVzc2lvbiBwYXR0ZXJuIG9mIG1hbnkgZ2VuZXMgaXMgc3ViamVjdCB0byBpbnRlcmFjdGlvbiBiZXR3ZWVuIHRoZSBnZW5lIGFuZCBpdHMgZW52aXJvbm1lbnQuIFRoaXMgaW5jbHVkZXMgdHJhaXRzIGNvbnRyb2xsZWQgYnkgYSBzaW5nbGUgZ2VuZSwgbGlrZSBQS1UgZGlzZWFzZS4=[Qq]

[x]

[restart]

[/qwiz]