1. You’ll see credit for completing this quiz in “Unit 3 Cumulative Assessment.”
  2. This same quiz can be completed for the same credit on the Biomania AP Bio App. Click here to download Biomania (free for students enrolled in a course with a teacher using

[qwiz style=” width: 600px !important; min-height: 450px !important;” quiz_timer=”true” random=”true” spaced_repetition=”false” qrecord_id=”sciencemusicvideosMeister1961-Cellular Respiration Click On Challenge” dataset_intro=”false” dataset=”cellular-respiration-click-on-challenge”]

[h] Cellular Respiration Click-On Challenge

[i] Note the timer in the top right corner. In the quiz that follows, aim for accuracy and speed.

[q json=”true” question_number=”1″ xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|2cc72646f3558″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Structure of ATP

Phosphate groups

Excellent. The phosphate groups are at number 3.

HINT FOR NEXT TIME: What letter does “Phosphate”  begin with.

Nice job. Number “1” is the 5-carbon sugar ribose.

HINT FOR NEXT TIME: Ribose is a monosaccharide with five carbon atoms. 

Nice! “2” is adenine

HINT FOR NEXT TIME: Adenine is a nitrogenous base. Look for nitrogen.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|728adc5037b3d” question_number=”2″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: ATP-ADP Cycle


Excellent! You clicked on ATP

HINT FOR NEXT TIME: ATP has three phosphates attached to the ribose sugar.

Way to go! That’s ADP.

HINT FOR NEXT TIME: ADP stands for adenosine diphosphate. Diphosphate means “two phosphate groups.”
Energy for transforming ADP + P into ATP

Fabulous. “A” represents energy for transforming ADP + P into ATP

No. Which arrow could represent energy for combining ADP and P into ATP?
Energy for cellular work

Way to go. B represents energy available for cellular work.

HINT FOR NEXT TIME: When ATP (with three phosphates) becomes ADP, energy becomes available for work.  What arrow shows ATP becoming ADP. 
Inorganic phosphate


No. Look for a phosphate group that’s not attached to a sugar and a base.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|723fc5d0beb3d” question_number=”3″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: The Four Phases of Respiration

Glycolysis (Click the number)

Nice! Number “1” represents glycolysis.

HINT FOR NEXT TIME: Glycolysis starts with glucose, and breaks it into two 3-carbon molecules.
The Link Reaction (Click the number)

Awesome. Number 2 represents the link reaction.

HINT FOR NEXT TIME: The link reaction brings pyruvic acid across the mitochondrial membranes. It links Glycolysis with the Krebs Cycle.
The Krebs Cycle (Click the number)

Magnificent! Number “3” represents the Krebs cycle.

HINT FOR NEXT TIME: It’s a cycle!
Oxidative phosporylation
(Click the number)

Way to go. Number 4 represents  oxidative phosphorylation.

HINT FOR NEXT TIME: This process requires oxygen (so look for O2) .

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|7216e1bfea73d” question_number=”4″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Glycolysis

Investment phase (Click the arrow)

Nice job. Arrow # 1 represents investment.


Excellent. G3P (F) is the 3-carbon molecule that results from cleavage.

HINT FOR NEXT TIME: This is the 3-carbon molecule that results from cleavage.
Cleavage phase (Click the arrow)

Terrific. “2” represents cleavage.

HINT FOR NEXT TIME: Look for where a six carbon molecule is broken apart to two 3-carbon molecules.
Harvest phase (Click the arrow)

Good job! “3” is the harvest phase

HINT FOR NEXT TIME: Look for where in the process the cell is gaining ATP and NADH.
ATP creation (click the letter)

Nice! “H” is where ATP is made through a substrate level phosphorylation.

HINT FOR NEXT TIME: Look for where ADP is being made into ATP.
Pyruvic acid

Nice job! Letter “I” is pyruvic acid (or pyruvate)

HINT FOR NEXT TIME: Look for the 3-carbon molecule that’s left at the end of the harvest phase
Redox reaction

Excellent. Conversion of NAD+ to NADH is reduction.

HINT FOR NEXT TIME: Look for where NAD+ is being converted to NADH 
Adding phosphates to glucose and fructose

Nice! “B” and “D” are adding phosphates to glucose and fructose.

HINT FOR NEXT TIME: This happens during the investment phase. Look for ATP becoming ADP.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|71c827eddd33d” question_number=”5″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Krebs cycle

Brings chemical energy into Krebs

Way to go. “A” is acetyl-CoA, which brings energy into the cycle.

HINT FOR NEXT TIME: Only one molecule is coming into the cycle from outside. Look on the top left.
The oxidized product of enzyme 8.

Nice job. Oxaloacetate (at “I”) is the oxidized product of enzyme 8.

HINT FOR NEXT TIME: Find enzyme 8. Its reduced product is NADH. What’s the oxidized product? 


A 6-carbon molecule is oxidized so that a mobile electron carrier can be reduced.

Yes! Oxidation of “C” powers reduction of NAD+ to NADH by enzyme 3.

HINT FOR NEXT TIME: It involves molecule “C” and enzyme 3. 
A 5-carbon molecule

Nice! Molecule D must have 5 carbons.

HINT FOR NEXT TIME: Enzyme 3 removes a CO2 from a 6 carbon molecule. What comes next?
The first four-carbon molecule in the cycle.

Terrific! Molecule “E” must be a 4 carbon molecule.

HINT FOR NEXT TIME: Enzyme 4 removes a CO2 from a 5 carbon molecule. What comes next?
Substrate level phosphorylation

Excellent. The enzymes at “5” catalyze a substrate level phosphorylation.

HINT FOR NEXT TIME: Krebs makes ATP by a substrate-level phosphorylation.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|719ffe20c033d” question_number=”6″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Link Reaction

The “food” that eukaryotic cells give to their mitochondria

Way to go. Eukaryotic cells feed their mitochondria with pyruvic acid (shown at “A”).

HINT FOR NEXT TIME: You’re looking for pyruvic acid, the energy/matter input. Look at the start of the arrow.
The mitochondrial membrane

Good! The mitochondrial membrane (inner and outer) is represented by “B”.

HINT FOR NEXT TIME: A membrane is a selectively permeable barrier. What looks like a barrier? 
An enzyme carrying out a redox reaction.

Awesome. The enzyme below “2” is reducing NAD+ to NADH.

HINT FOR NEXT TIME: Look for the enzyme that’s reducing NAD+ to NADH.
The input for the Krebs cycle

Nice! Acetyl CoA (at D) is the energy/matter input for the Krebs cycle.

HINT FOR NEXT TIME: You’re looking for a two carbon molecule attached to  acetyl CoA. Look for “S-CoA”

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|712e579c56f3d” question_number=”7″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Oxidative phosphorylation: Key Mitochondrial Regions


Yes. The cytoplasm is represents by region “A.”

HINT FOR NEXT TIME: The cytoplasm is outside the outer mitochondrial membrane.
The outer mitochondrial membrane

Nice! “B” represents the outer membrane.

HINT FOR NEXT TIME: The inner membrane has many proteins and channels. The outer one is represented here by a plain phospholipid bilayer.
The intermembrane space.

Nice! Region “C” is the intermembrane space.

HINT FOR NEXT TIME: The intermembrane space is in between the inner and outer membranes.
The mitochondrial matrix.

Nice. The mitochondrial matrix is represented by region “E.”

HINT FOR NEXT TIME: The matrix is like the cytoplasm of the mitochondria. It’s the innermost space. 

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|710afb27c033d” question_number=”8″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Oxidative phosphorylation

Proton pumps

Excellent. Proton pumps are represented by number 3.

HINT FOR NEXT TIME: Find arrows that move protons (H+) from low to high concentration.
ATP synthase channel.

Great! ATP synthase is represented by number 5.

HINT FOR NEXT TIME: ATP synthase is a channel that lets protons diffuse through.
Area with lowest pH

Good work. The intermembrane space has the lowest pH

HINT FOR NEXT TIME: Find an area with a lot of protons.
Reduced molecules that power the ETC.

Nice job. NADH and FADH2 are the reduced molecules that power the ETC.

HINT FOR NEXT TIME: Look for the molecules that donate electrons to the electron transport chain (ETC).

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|70c0546a81f3d” question_number=”9″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Where cellular respiration happens

Where glycolysis happens

Nice. Glycolysis happens in the cytoplasm (region 3)

HINT FOR NEXT TIME: Glycolysis happens in the cytoplasm.
Where the Krebs cycle happens.

Great! Krebs happens in the matrix (at 5)

HINT FOR NEXT TIME: Krebs happens in the mitochondrial matrix, which is like the cytoplasm of the mitochondrion.
Where protons get pumped to.

Awesome. Protons get pumped to the intermembrane space (at 7).

HINT FOR NEXT TIME: Protons get pumped to the intermembrane space.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|703685eabb33d” question_number=”10″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: The Four Phases of Respiration: Key Molecules


Nice. Acetyl-CoA is represented by “E.”

HINT FOR NEXT TIME:  <span style=”font-size: 13.3333px;”> Acetyl-CoA comes out of the link reaction and goes into the Krebs cycle. </span style=”font-size: 13.3333px;”>


Pyruvic acid (pyruvate)

Nice! Molecule “D” is pyruvic acid (pyruvate)

HINT FOR NEXT TIME: Look for a 3-carbon molecule that comes out of glycolysis and goes into the link reaction.

Nice. Molecule “A” is glucose.

HINT FOR NEXT TIME: Look at the start of glycolysis.


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