1. You’ll see credit for completing this quiz in “Unit 3 Cumulative Assessment.”
  2. This same quiz can be completed for the same credit on the Biomania AP Bio App. Click here to download Biomania (free for students enrolled in a course with a teacher using

[qwiz style=” width: 600px !important; min-height: 450px !important;” quiz_timer=”true” random=”true” spaced_repetition=”false” qrecord_id=”sciencemusicvideosMeister1961-Cellular Respiration Click On Challenge” dataset_intro=”false” dataset=”cellular-respiration-click-on-challenge”]

[h] Cellular Respiration Click-On Challenge

[i] Note the timer in the top right corner. In the quiz that follows, aim for accuracy and speed.

[q json=”true” question_number=”1″ xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|2cc72646f3558″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Structure of ATP

Phosphate groups

Excellent. The phosphate groups are at number 3.

HINT: What letter does “Phosphate”  begin with.

Nice job. Number “1” is the 5-carbon sugar ribose.

HINT: Ribose is a monosaccharide with five carbon atoms. 

Nice! “2” is adenine

HINT: Adenine is a nitrogenous base. Look for nitrogen.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|728adc5037b3d” question_number=”2″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: ATP-ADP Cycle


Excellent! You clicked on ATP

HINT: ATP has three phosphates attached to the ribose sugar.

Way to go! That’s ADP.

HINT: ADP stands for adenosine diphosphate. Diphosphate means “two phosphate groups.”
Energy for transforming ADP + P into ATP

Fabulous. “A” represents energy for transforming ADP + P into ATP

No. Which arrow could represent energy for combining ADP and P into ATP?
Energy for cellular work

Way to go. B represents energy available for cellular work.

HINT: When ATP (with three phosphates) becomes ADP, energy becomes available for work.  What arrow shows ATP becoming ADP. 
Inorganic phosphate


No. Look for a phosphate group that’s not attached to a sugar and a base.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|723fc5d0beb3d” question_number=”3″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: The Four Phases of Respiration

Glycolysis (Click the number)

Nice! Number “1” represents glycolysis.

HINT: Glycolysis starts with glucose, and breaks it into two 3-carbon molecules.
The Link Reaction (Click the number)

Awesome. Number 2 represents the link reaction.

HINT: The link reaction brings pyruvic acid across the mitochondrial membranes. It links Glycolysis with the Krebs Cycle.
The Krebs Cycle (Click the number)

Magnificent! Number “3” represents the Krebs cycle.

HINT: It’s a cycle!
Oxidative phosporylation
(Click the number)

Way to go. Number 4 represents  oxidative phosphorylation.

HINT: This process requires oxygen (so look for O2) .

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|7216e1bfea73d” question_number=”4″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Glycolysis

Investment phase (Click the arrow)

Nice job. Arrow # 1 represents investment.


Excellent. G3P (F) is the 3-carbon molecule that results from cleavage.

HINT: This is the 3-carbon molecule that results from cleavage.
Cleavage phase (Click the arrow)

Terrific. “2” represents cleavage.

HINT: Look for where a six carbon molecule is broken apart to two 3-carbon molecules.
Harvest phase (Click the arrow)

Good job! “3” is the harvest phase

HINT: Look for where in the process the cell is gaining ATP and NADH.
ATP creation (click the letter)

Nice! “H” is where ATP is made through a substrate level phosphorylation.

HINT: Look for where ADP is being made into ATP.
Pyruvic acid

Nice job! Letter “I” is pyruvic acid (or pyruvate)

HINT: Look for the 3-carbon molecule that’s left at the end of the harvest phase
Redox reaction

Excellent. Conversion of NAD+ to NADH is reduction.

HINT: Look for where NAD+ is being converted to NADH 
Adding phosphates to glucose and fructose

Nice! “B” and “D” are adding phosphates to glucose and fructose.

HINT: This happens during the investment phase. Look for ATP becoming ADP.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|71c827eddd33d” question_number=”5″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Krebs cycle

Brings chemical energy into Krebs

Way to go. “A” is acetyl-CoA, which brings energy into the cycle.

HINT: Only one molecule is coming into the cycle from outside. Look on the top left.
The oxidized product of enzyme 8.

Nice job. Oxaloacetate (at “I”) is the oxidized product of enzyme 8.

HINT: Find enzyme 8. Its reduced product is NADH. What’s the oxidized product? 


A 6-carbon molecule is oxidized so that a mobile electron carrier can be reduced.

Yes! Oxidation of “C” powers reduction of NAD+ to NADH by enzyme 3.

HINT: It involves molecule “C” and enzyme 3. 
A 5-carbon molecule

Nice! Molecule D must have 5 carbons.

HINT: Enzyme 3 removes a CO2 from a 6 carbon molecule. What comes next?
The first four-carbon molecule in the cycle.

Terrific! Molecule “E” must be a 4 carbon molecule.

HINT: Enzyme 4 removes a CO2 from a 5 carbon molecule. What comes next?
Substrate level phosphorylation

Excellent. The enzymes at “5” catalyze a substrate level phosphorylation.

HINT: Krebs makes ATP by a substrate-level phosphorylation.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|719ffe20c033d” question_number=”6″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Link Reaction

The “food” that eukaryotic cells give to their mitochondria

Way to go. Eukaryotic cells feed their mitochondria with pyruvic acid (shown at “A”).

HINT: You’re looking for pyruvic acid, the energy/matter input. Look at the start of the arrow.
The mitochondrial membrane

Good! The mitochondrial membrane (inner and outer) is represented by “B”.

HINT: A membrane is a selectively permeable barrier. What looks like a barrier? 
An enzyme carrying out a redox reaction.

Awesome. The enzyme below “2” is reducing NAD+ to NADH.

HINT: Look for the enzyme that’s reducing NAD+ to NADH.
The input for the Krebs cycle

Nice! Acetyl CoA (at D) is the energy/matter input for the Krebs cycle.

HINT: You’re looking for a two carbon molecule attached to  acetyl CoA. Look for “S-CoA”

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|712e579c56f3d” question_number=”7″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Oxidative phosphorylation: Key Mitochondrial Regions


Yes. The cytoplasm is represents by region “A.”

HINT: The cytoplasm is outside the outer mitochondrial membrane.
The outer mitochondrial membrane

Nice! “B” represents the outer membrane.

HINT: The inner membrane has many proteins and channels. The outer one is represented here by a plain phospholipid bilayer.
The intermembrane space.

Nice! Region “C” is the intermembrane space.

HINT: The intermembrane space is in between the inner and outer membranes.
The mitochondrial matrix.

Nice. The mitochondrial matrix is represented by region “E.”

HINT: The matrix is like the cytoplasm of the mitochondria. It’s the innermost space. 

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|710afb27c033d” question_number=”8″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Oxidative phosphorylation

Proton pumps

Excellent. Proton pumps are represented by number 3.

HINT: Find arrows that move protons (H+) from low to high concentration.
ATP synthase channel.

Great! ATP synthase is represented by number 5.

HINT: ATP synthase is a channel that lets protons diffuse through.
Area with lowest pH

Good work. The intermembrane space has the lowest pH

HINT: Find an area with a lot of protons.
Reduced molecules that power the ETC.

Nice job. NADH and FADH2 are the reduced molecules that power the ETC.

HINT: Look for the molecules that donate electrons to the electron transport chain (ETC).

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|70c0546a81f3d” question_number=”9″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: Where cellular respiration happens

Where glycolysis happens

Nice. Glycolysis happens in the cytoplasm (region 3)

HINT: Glycolysis happens in the cytoplasm.
Where the Krebs cycle happens.

Great! Krebs happens in the matrix (at 5)

HINT: Krebs happens in the mitochondrial matrix, which is like the cytoplasm of the mitochondrion.
Where protons get pumped to.

Awesome. Protons get pumped to the intermembrane space (at 7).

HINT: Protons get pumped to the intermembrane space.

[q json=”true” xx=”2″ dataset_id=”cellular-respiration-click-on-challenge|703685eabb33d” question_number=”10″ hotspot_user_interaction=”label_prompt” show_hotspots=”” unit=”3.Cellular_Energetics” topic=”3.6.Cellular_Respiration”] TOPIC: The Four Phases of Respiration: Key Molecules


Nice. Acetyl-CoA is represented by “E.”

HINT:  <span style=”font-size: 13.3333px;”> Acetyl-CoA comes out of the link reaction and goes into the Krebs cycle. </span style=”font-size: 13.3333px;”>


Pyruvic acid (pyruvate)

Nice! Molecule “D” is pyruvic acid (pyruvate)

HINT: Look for a 3-carbon molecule that comes out of glycolysis and goes into the link reaction.

Nice. Molecule “A” is glucose.

HINT: Look at the start of glycolysis.


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